PDBsum entry 3v17

Oxidoreductase

PDB id: 3v17

Contents

Protein chains

276 a.a.

Ligands

AKG ×4

Waters ×402

PDB id:

3v17

Name:

Oxidoreductase

Title:

Crystal structure of the fe(ii)/alpha-ketoglutarate dependent taurine dioxygenase from pseudomonas putida kt2440

Structure:

Alpha-ketoglutarate-dependent taurine dioxygenase. Chain: a, c, b, d. Engineered: yes

Source:

Pseudomonas putida. Organism_taxid: 160488. Strain: kt2440. Gene: pp0230, pp_0230, taud. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.57Å R-factor: 0.180 R-free: 0.225

Authors:

S.H.Knauer,H.Dobbek

Key ref:

S.H.Knauer et al. (2012). The Fe(II)/α-ketoglutarate-dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramers. Febs J, 279, 816-831. PubMed id: 22221834

Date:

09-Dec-11 Release date: 18-Jan-12

Protein chains

Q88RA3  (Q88RA3_PSEPK) -  Alpha-ketoglutarate-dependent taurine dioxygenase from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)

Seq: 277 a.a.

Struc: 276 a.a.

Enzyme reactions

• Enzyme class: E.C.1.14.11.17 - taurine dioxygenase.
• Reaction: taurine + 2-oxoglutarate + O2 = aminoacetaldehyde + sulfite + succinate + CO2 + H⁺

taurine (Bound ligand (Het Group name = AKG) corresponds exactly) + 2-oxoglutarate + O2 = aminoacetaldehyde + sulfite + succinate + CO2 + H(+)

• Cofactor: Fe(2+); L-ascorbate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Febs J 279:816-831 (2012)

PubMed id: 22221834

The Fe(II)/α-ketoglutarate-dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramers.

S.H.Knauer, O.Hartl-Spiegelhauer, S.Schwarzinger, P.Hänzelmann, H.Dobbek.

ABSTRACT

No abstract given.