PDBsum entry 3uqs

Transferase

PDB id: 3uqs

Contents

Protein chains

478 a.a.

Ligands

SO4 ×13

Waters ×1355

PDB id:

3uqs

Name:

Transferase

Title:

Crystal structures of murine norovirus RNA-dependent RNA polymerase

Structure:

RNA-dependent RNA polymerase. Chain: a, b, c. Fragment: unp residues 1174-1684. Engineered: yes

Source:

Murine norovirus. Organism_taxid: 223997. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.00Å R-factor: 0.188 R-free: 0.227

Authors:

M.Milani,E.Mastrangelo,M.Bolognesi

Key ref:

E.Mastrangelo et al. (2012). Structure-based inhibition of Norovirus RNA-dependent RNA polymerases. J Mol Biol, 419, 198-210. PubMed id: 22446684

Date:

21-Nov-11 Release date: 02-May-12

Protein chains

Q80J95  (Q80J95_9CALI) -  Genome polyprotein from Norovirus (isolate Mouse/NoV/United States/MNV1/2002/GV)

Seq: 1687 a.a.

Struc: 478 a.a.

Enzyme reactions

• Enzyme class: E.C.?

J Mol Biol 419:198-210 (2012)

PubMed id: 22446684

Structure-based inhibition of Norovirus RNA-dependent RNA polymerases.

E.Mastrangelo, M.Pezzullo, D.Tarantino, R.Petazzi, F.Germani, D.Kramer, I.Robel, J.Rohayem, M.Bolognesi, M.Milani.

ABSTRACT

No abstract given.