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PDBsum entry 3uj4
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Signaling protein
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PDB id
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3uj4
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PDB id:
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| Name: |
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Signaling protein
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Title:
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Crystal structure of the apo-inositol 1,4,5-trisphosphate receptor
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Structure:
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Inositol 1,4,5-trisphosphate receptor type 1. Chain: a, b. Synonym: ip-3-r, ip3r 1, insp3r1, type 1 inositol 1,4,5-trisphosphate receptor, type 1 insp3 receptor. Engineered: yes
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Source:
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Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: itpr1, insp3r. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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3.00Å
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R-factor:
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0.211
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R-free:
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0.256
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Authors:
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M.Ikura,M.D.Seo,N.Ishiyama,P.Stathopulos
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Key ref:
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M.D.Seo
et al.
(2012).
Structural and functional conservation of key domains in InsP3 and ryanodine receptors.
Nature,
483,
108-112.
PubMed id:
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Date:
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07-Nov-11
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Release date:
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15-Feb-12
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PROCHECK
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Headers
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References
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P29994
(ITPR1_RAT) -
Inositol 1,4,5-trisphosphate receptor type 1 from Rattus norvegicus
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Seq:
Struc:
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2750 a.a.
486 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 11 residue positions (black
crosses)
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Nature
483:108-112
(2012)
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PubMed id:
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Structural and functional conservation of key domains in InsP3 and ryanodine receptors.
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M.D.Seo,
S.Velamakanni,
N.Ishiyama,
P.B.Stathopulos,
A.M.Rossi,
S.A.Khan,
P.Dale,
C.Li,
J.B.Ames,
M.Ikura,
C.W.Taylor.
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ABSTRACT
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Links
