PDBsum entry 3ss7

Lyase

PDB id: 3ss7

Contents

Protein chain

437 a.a.

Ligands

GOL

PLP

Metals

__K

Waters ×680

PDB id:

3ss7

Name:

Lyase

Title:

Crystal structure of holo d-serine dehydratase from escherichia coli at 1.55 a resolution

Structure:

D-serine dehydratase. Chain: x. Synonym: d-serine deaminase, dsd. Engineered: yes

Source:

Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: b2366, dsda, dsda b2366jw2393, jw2363. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.55Å R-factor: 0.161 R-free: 0.194

Authors:

D.V.Urusova,M.N.Isupov,S.V.Antonyuk,G.S.Kachalova,A.A.Vagin, A.A.Lebedev,G.P.Bourenkov,Z.Dauter,H.D.Bartunik,W.R.Melik-Adamyan, T.D.Mueller,K.D.Schnackerz

Key ref:

D.V.Urusova et al. (2012). Crystal structure of D-serine dehydratase from Escherichia coli. Biochim Biophys Acta, 1824, 422-432. PubMed id: 22197591

Date:

07-Jul-11 Release date: 18-Jan-12

Protein chain

P00926  (SDHD_ECOLI) -  D-serine dehydratase from Escherichia coli (strain K12)

Seq: 442 a.a.

Struc: 437 a.a.

Enzyme reactions

• Enzyme class: E.C.4.3.1.18 - D-serine ammonia-lyase.
• Reaction: D-serine = pyruvate + NH4⁺

D-serine = pyruvate (Bound ligand (Het Group name = GOL) matches with 71.43% similarity) + NH4(+)

• Cofactor: Pyridoxal 5'-phosphate

Pyridoxal 5'-phosphate (Bound ligand (Het Group name = PLP) matches with 93.75% similarity)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Biochim Biophys Acta 1824:422-432 (2012)

PubMed id: 22197591

Crystal structure of D-serine dehydratase from Escherichia coli.

D.V.Urusova, M.N.Isupov, S.Antonyuk, G.S.Kachalova, G.Obmolova, A.A.Vagin, A.A.Lebedev, G.P.Burenkov, Z.Dauter, H.D.Bartunik, V.S.Lamzin, W.R.Melik-Adamyan, T.D.Mueller, K.D.Schnackerz.

ABSTRACT

No abstract given.