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PDBsum entry 3ryt
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Signaling protein
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PDB id
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3ryt
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Contents |
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532 a.a.
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531 a.a.
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174 a.a.
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PDB id:
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| Name: |
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Signaling protein
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Title:
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The plexin a1 intracellular region in complex with rac1
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Structure:
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Plexin-a1. Chain: a, b. Fragment: intracellular region (unp residues 1269-1894). Synonym: plex 1, plexin-1. Engineered: yes. Ras-related c3 botulinum toxin substrate 1. Chain: c. Fragment: unp residues 1-177. Synonym: rac1, cell migration-inducing gene 5 protein, ras-like
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Source:
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Mus musculus. Mouse. Organism_taxid: 10090. Gene: kiaa4053, plexin a1, plxna1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
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Resolution:
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3.58Å
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R-factor:
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0.270
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R-free:
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0.340
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Authors:
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X.Zhang,H.He
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Key ref:
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Y.Wang
et al.
(2012).
Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization.
Sci Signal,
5,
ra6.
PubMed id:
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Date:
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11-May-11
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Release date:
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18-Jan-12
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PROCHECK
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Headers
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References
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P70206
(PLXA1_MOUSE) -
Plexin-A1 from Mus musculus
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Seq:
Struc:
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1894 a.a.
532 a.a.
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Enzyme class:
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Chain C:
E.C.3.6.5.2
- small monomeric GTPase.
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Reaction:
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GTP + H2O = GDP + phosphate + H+
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GTP
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+
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H2O
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=
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GDP
Bound ligand (Het Group name = )
matches with 81.82% similarity
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+
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phosphate
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+
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H(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Sci Signal
5:ra6
(2012)
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PubMed id:
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Plexins are GTPase-activating proteins for Rap and are activated by induced dimerization.
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Y.Wang,
H.He,
N.Srivastava,
S.Vikarunnessa,
Y.B.Chen,
J.Jiang,
C.W.Cowan,
X.Zhang.
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ABSTRACT
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Literature references that cite this PDB file's key reference
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PubMed id
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Reference
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B.J.Janssen,
T.Malinauskas,
G.A.Weir,
M.Z.Cader,
C.Siebold,
and
E.Y.Jones
(2012).
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex.
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Nat Struct Mol Biol,
19,
1293-1299.
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PDB codes:
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The most recent references are shown first.
Citation data come partly from CiteXplore and partly
from an automated harvesting procedure. Note that this is likely to be
only a partial list as not all journals are covered by
either method. However, we are continually building up the citation data
so more and more references will be included with time.
Where a reference describes a PDB structure, the PDB
codes are
shown on the right.
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