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PDBsum entry 3rpl
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PDB id:
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Hydrolase
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Title:
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D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase of synechocystis sp. Pcc 6803 in complex with fructose-1,6- bisphosphate
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Structure:
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D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7- bisphosphatase. Chain: a, c, d. Synonym: fbpase class 2/sbpase. Engineered: yes. D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7- bisphosphatase. Chain: b. Synonym: fbpase class 2/sbpase.
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Source:
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Synechocystis. Organism_taxid: 1148. Strain: pcc 6803. Gene: slr2094. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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2.40Å
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R-factor:
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0.168
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R-free:
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0.207
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Authors:
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X.Hu,D.Hui,F.Lingling,W.Jian
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Key ref:
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X.Hu
and
f.lingling
New insights into the structural and interactional ba a promising route towards fructose-1,6-/Sedoheptulose-1,7-Bisphosphatases contr.
To be published,
.
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Date:
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26-Apr-11
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Release date:
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02-May-12
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PROCHECK
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Headers
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References
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P73922
(FBSB_SYNY3) -
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase from Synechocystis sp. (strain ATCC 27184 / PCC 6803 / Kazusa)
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Seq:
Struc:
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345 a.a.
347 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class 1:
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E.C.3.1.3.11
- fructose-bisphosphatase.
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Pathway:
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Pentose Phosphate Pathway (later stages)
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Reaction:
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beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate
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beta-D-fructose 1,6-bisphosphate
Bound ligand (Het Group name = )
corresponds exactly
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+
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H2O
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=
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beta-D-fructose 6-phosphate
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+
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phosphate
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Enzyme class 2:
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E.C.3.1.3.37
- sedoheptulose-bisphosphatase.
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Pathway:
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Reaction:
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D-sedoheptulose 1,7-bisphosphate + H2O = D-sedoheptulose 7-phosphate + phosphate
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D-sedoheptulose 1,7-bisphosphate
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+
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H2O
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=
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D-sedoheptulose 7-phosphate
Bound ligand (Het Group name = )
matches with 72.73% similarity
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+
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phosphate
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
