PDBsum entry 3rga

Isomerase

PDB id: 3rga

Contents

Protein chain

281 a.a.

Ligands

LSB

ILD

GOL ×2

ACT ×2

MOH ×2

FMT ×3

Metals

_NA

Waters ×170

PDB id:

3rga

Name:

Isomerase

Title:

Crystal structure of epoxide hydrolase for polyether lasalocid a biosynthesis

Structure:

Epoxide hydrolase. Chain: a. Engineered: yes

Source:

Streptomyces lasaliensis. Organism_taxid: 324833. Gene: lasb, lsd19. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.59Å R-factor: 0.174 R-free: 0.192

Authors:

K.Hotta,I.I.Mathews,X.Chen,C.-Y.Kim

Key ref:

K.Hotta et al. (2012). Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis. Nature, 483, 355-358. PubMed id: 22388816

Date:

08-Apr-11 Release date: 07-Mar-12

Protein chain

B6ZK72  (LSD19_STRLS) -  Epoxide hydrolase LasB from Streptomyces lasalocidi

Seq: 282 a.a.

Struc: 281 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.5.5.1.- - ?????

Nature 483:355-358 (2012)

PubMed id: 22388816

Enzymatic catalysis of anti-Baldwin ring closure in polyether biosynthesis.

K.Hotta, X.Chen, R.S.Paton, A.Minami, H.Li, K.Swaminathan, I.I.Mathews, K.Watanabe, H.Oikawa, K.N.Houk, C.Y.Kim.

ABSTRACT

No abstract given.