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PDBsum entry 3rc0
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PDB id:
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Transferase
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Title:
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Human setd6 in complex with rela lys310 peptide
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Structure:
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N-lysine methyltransferase setd6. Chain: a, b. Synonym: set domain-containing protein 6. Engineered: yes. Transcription factor p65 peptide. Chain: p, q. Fragment: unp q04206 residues 302-316. Synonym: nuclear factor nf-kappa-b p65 subunit, nuclear factor of kappa light polypeptide gene enhancer in b-cells 3.
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: setd6. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized. The sequence of the peptide is naturally found in homo sapiens (human).
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Resolution:
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2.19Å
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R-factor:
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0.169
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R-free:
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0.234
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Authors:
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Y.Chang,D.Levy,J.R.Horton,J.Peng,X.Zhang,O.Gozani,X.Cheng
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Key ref:
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Y.Chang
et al.
(2011).
Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res,
39,
6380-6389.
PubMed id:
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Date:
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30-Mar-11
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Release date:
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25-May-11
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PROCHECK
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Headers
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References
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Q8TBK2
(SETD6_HUMAN) -
N-lysine methyltransferase SETD6 from Homo sapiens
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Seq:
Struc:
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473 a.a.
420 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Nucleic Acids Res
39:6380-6389
(2011)
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PubMed id:
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Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
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Y.Chang,
D.Levy,
J.R.Horton,
J.Peng,
X.Zhang,
O.Gozani,
X.Cheng.
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ABSTRACT
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Links
