 |
PDBsum entry 3r5m
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Transcription/transcription agonist
|
PDB id
|
|
|
|
3r5m
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Transcription/transcription agonist
|
|
|
Title:
|
|
Crystal structure of rxralphalbd complexed with the agonist magnolol
|
|
Structure:
|
|
Retinoic acid receptor rxr-alpha. Chain: a, c. Fragment: ligand binding domain (unp residues 223-462). Synonym: nuclear receptor subfamily 2 group b member 1, retinoid x receptor alpha. Engineered: yes. Nuclear receptor coactivator 2. Chain: b, d. Fragment: unp residues 687-696.
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Gene: rxra, nr2b1. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Organism_taxid: 9606
|
|
Resolution:
|
|
|
2.80Å
|
R-factor:
|
0.252
|
R-free:
|
0.293
|
|
|
Authors:
|
|
H.Zhang,L.Chen,J.Chen,L.Hu,H.Jiang,X.Shen
|
|
Key ref:
|
|
H.Zhang
et al.
(2011).
Molecular determinants of magnolol targeting both RXRα and PPARγ.
Plos One,
6,
e28253.
PubMed id:
|
|
|
Date:
|
|
|
18-Mar-11
|
Release date:
|
08-Feb-12
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
P19793
(RXRA_HUMAN) -
Retinoic acid receptor RXR-alpha from Homo sapiens
|
|
|
|
Seq:
Struc:
|
|
|
|
462 a.a.
215 a.a.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
|
|
|
|
|
|
| |
|
|
Plos One
6:e28253
(2011)
|
|
PubMed id:
|
|
|
|
|
|
| |
|
Molecular determinants of magnolol targeting both RXRα and PPARγ.
|
|
H.Zhang,
X.Xu,
L.Chen,
J.Chen,
L.Hu,
H.Jiang,
X.Shen.
|
|
|
|
|
| |
ABSTRACT
|
|
|
|
| |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
 |
 |
 |
|
Links
