PDBsum entry 3r4t

Transferase

PDB id: 3r4t

Contents

Protein chain

444 a.a.

Ligands

MPD

Metals

_NA

_CL ×4

Waters ×206

PDB id:

3r4t

Name:

Transferase

Title:

Crystal structure of 4-aminobutyrate aminotransferase gabt from mycobacterium marinum covalently bound to pyridoxal phosphate

Structure:

4-aminobutyrate aminotransferase gabt. Chain: a. Engineered: yes

Source:

Mycobacterium marinum. Organism_taxid: 216594. Strain: atcc baa-535 / m. Gene: gabt, mmar_2118. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.50Å R-factor: 0.153 R-free: 0.191

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

L.Baugh et al. (2015). Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (edinb), 95, 142-148. PubMed id: 25613812 DOI: 10.1016/j.tube.2014.12.003

Date:

17-Mar-11 Release date: 30-Mar-11

Protein chain

B2HN70  (B2HN70_MYCMM) -  4-aminobutyrate aminotransferase GabT from Mycobacterium marinum (strain ATCC BAA-535 / M)

Seq: 446 a.a.

Struc: 444 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

DOI no: 10.1016/j.tube.2014.12.003

Tuberculosis (edinb) 95:142-148 (2015)

PubMed id: 25613812

Increasing the structural coverage of tuberculosis drug targets.

L.Baugh, I.Phan, D.W.Begley, M.C.Clifton, B.Armour, D.M.Dranow, B.M.Taylor, M.M.Muruthi, J.Abendroth, J.W.Fairman, D.Fox, S.H.Dieterich, B.L.Staker, A.S.Gardberg, R.Choi, S.N.Hewitt, A.J.Napuli, J.Myers, L.K.Barrett, Y.Zhang, M.Ferrell, E.Mundt, K.Thompkins, N.Tran, S.Lyons-Abbott, A.Abramov, A.Sekar, D.Serbzhinskiy, D.Lorimer, G.W.Buchko, R.Stacy, L.J.Stewart, T.E.Edwards, W.C.Van Voorhis, P.J.Myler.

ABSTRACT

No abstract given.