PDBsum entry 3q5s

Transcription/DNA

PDB id: 3q5s

Contents

Protein chain

275 a.a.

DNA/RNA

Ligands

ACH

GOL

Waters ×9

PDB id:

3q5s

Name:

Transcription/DNA

Title:

Crystal structure of bmrr bound to acetylcholine

Structure:

Multidrug-efflux transporter 1 regulator. Chain: a. Engineered: yes. 23 bp promoter DNA. Chain: b. Engineered: yes

Source:

Bacillus subtilis. Organism_taxid: 1423. Gene: bmrr, bmr1r, bsu24020. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: 23 bp promoter of bmr efflux gene synthesized by idt

Resolution:

3.10Å R-factor: 0.227 R-free: 0.276

Authors:

S.Bachas,C.Eginton,G.Gunio,H.Wade

Key ref:

S.Bachas et al. (2011). Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR. Proc Natl Acad Sci U S A, 108, 11046-11051. PubMed id: 21690368

Date:

29-Dec-10 Release date: 15-Jun-11

Protein chain

P39075  (BMRR_BACSU) -  Multidrug-efflux transporter 1 regulator from Bacillus subtilis (strain 168)

Seq: 278 a.a.

Struc: 275 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

DNA/RNA chain

G-A-C-C-C-T-C-C-C-C-T-T-A-G-G-G-G-A-G-G-G-T-C 23 bases

Proc Natl Acad Sci U S A 108:11046-11051 (2011)

PubMed id: 21690368

Structural contributions to multidrug recognition in the multidrug resistance (MDR) gene regulator, BmrR.

S.Bachas, C.Eginton, D.Gunio, H.Wade.

ABSTRACT

No abstract given.