PDBsum entry 3poc

Hydrolase/hydrolase inhibitor

PDB id: 3poc

Contents

Protein chains

664 a.a. *

Ligands

GLC-GLC-AC1

GLC

AC1 ×2

GOL

Waters ×516

* Residue conservation analysis

PDB id:

3poc

Name:

Hydrolase/hydrolase inhibitor

Title:

The crystal structure of the d307a mutant of alpha-glucosidase (family 31) from ruminococcus obeum atcc 29174 in complex with acarbose

Structure:

Alpha-glucosidase. Chain: a, b. Engineered: yes. Mutation: yes

Source:

Ruminococcus obeum. Organism_taxid: 411459. Strain: atcc 29174. Gene: rumobe_03919. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.99Å R-factor: 0.171 R-free: 0.225

Authors:

K.Tan,C.Tesar,R.Wilton,L.Keigher,G.Babnigg,A.Joachimiak,Midwest Center For Structural Genomics (Mcsg)

Key ref:

K.Tan et al. The crystal structure of the d307a mutant of alpha-Glucosidase (family 31) from ruminococcus obeum 29174 in complex with acarbose. To be published, .

Date:

22-Nov-10 Release date: 26-Jan-11

Supersedes:

3nqq

Protein chains

A5ZY13  (A5ZY13_9FIRM) -  Glycosyl hydrolase, family 31 from Blautia obeum ATCC 29174

Seq: 663 a.a.

Struc: 664 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.2.1.- - ?????