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PDBsum entry 3pii
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protein ligands metals Protein-protein interface(s) links
Oxidoreductase PDB id
3pii

 

 

 

 

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Contents
Protein chains
337 a.a.
Ligands
BMD ×4
SO4 ×4
Metals
_ZN ×8
Waters ×3
PDB id:
3pii
Name: Oxidoreductase
Title: Crystal structure of mutant of ht- alcohol dehydrogenase with substrate analogue butyramide
Structure: Alcohol dehydrogenase. Chain: a, c, b, d. Synonym: adh-ht. Engineered: yes. Mutation: yes
Source: Geobacillus stearothermophilus. Bacillus thermoliquefaciens. Organism_taxid: 1422. Gene: adh-ht. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.90Å     R-factor:   0.210     R-free:   0.286
Authors: M.Dong,B.J.Bahnson
Key ref: M.Dong and b.j.bahnson Crystal structure of mutant of ht- Alcohol dehydrogen. To be published, .
Date:
06-Nov-10     Release date:   09-Nov-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P42328  (ADH3_GEOSE) -  Alcohol dehydrogenase from Geobacillus stearothermophilus
Seq:
Struc: 		339 a.a.
337 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 1 residue position (black cross)

 Enzyme reactions 
   Enzyme class: E.C.1.1.1.1  - alcohol dehydrogenase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction:
1. a primary alcohol + NAD+ = an aldehyde + NADH + H+
2. a secondary alcohol + NAD+ = a ketone + NADH + H+
primary alcohol
 + NAD(+)
 = aldehyde
 + NADH
 + H(+)
secondary alcohol
 + NAD(+)
 = ketone
 + NADH
 + H(+)
      Cofactor: Zn(2+) or Fe cation
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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