PDBsum entry 3p5t

RNA binding protein

PDB id: 3p5t

Contents

Protein chains

(+ 0 more) 196 a.a. *

76 a.a. *

81 a.a. *

Waters ×248

* Residue conservation analysis

PDB id:

3p5t

Name:

RNA binding protein

Title:

Cfim25-cfim68 complex

Structure:

Cleavage and polyadenylation specificity factor subunit 5. Chain: a, b, c, d, e, f. Fragment: unp residues 34-227. Synonym: cleavage factor im 25, cleavage and polyadenylation specificity factor 25 kda subunit, cpsf 25 kda subunit, nucleoside diphosphate-linked moiety x motif 21, nudix motif 21, pre-mRNA cleavage factor im 25 kda subunit. Engineered: yes. Cleavage and polyadenylation specificity factor subunit 6.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: nudt21, cfim25, cpsf25, cpsf5. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: cpsf6, cfim68. Expression_system_taxid: 562

Resolution:

2.70Å R-factor: 0.216 R-free: 0.265

Authors:

H.Li,S.Tong,X.Li,H.Shi,Y.Gao,H.Ge,L.Niu,M.Teng

Key ref:

H.Li et al. Structural basis of pre-Mrna recognition by the human cleavage factor im complex. To be published, . PubMed id: 21483454

Date:

11-Oct-10 Release date: 03-Nov-10

Protein chains

O43809  (CPSF5_HUMAN) -  Cleavage and polyadenylation specificity factor subunit 5 from Homo sapiens

Seq: 227 a.a.

Struc: 196 a.a.

Protein chain

Q16630  (CPSF6_HUMAN) -  Cleavage and polyadenylation specificity factor subunit 6 from Homo sapiens

Seq: 551 a.a.

Struc: 76 a.a.*

Protein chains

Q16630  (CPSF6_HUMAN) -  Cleavage and polyadenylation specificity factor subunit 6 from Homo sapiens

Seq: 551 a.a.

Struc: 81 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)