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PDBsum entry 3p5e
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Sugar binding protein
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PDB id
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3p5e
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Sugar binding protein
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Title:
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Structure of the carbohydrate-recognition domain of human langerin with man4 (man alpha1-3(man alpha1-6)man alpha1-6man)
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Structure:
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C-type lectin domain family 4 member k. Chain: a, b, c, d. Fragment: langerin crd (unp residues 193-328). Synonym: langerin. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: cd207, clec4k. Expressed in: escherichia coli. Expression_system_taxid: 83333.
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Resolution:
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1.70Å
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R-factor:
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0.175
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R-free:
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0.212
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Authors:
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H.Feinberg,M.E.Taylor,N.Razi,R.Mcbride,Y.A.Knirel,S.A.Graham, K.Drickamer,W.I.Weis
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Key ref:
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H.Feinberg
et al.
(2011).
Structural basis for langerin recognition of diverse pathogen and mammalian glycans through a single binding site.
J Mol Biol,
405,
1027-1039.
PubMed id:
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Date:
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08-Oct-10
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Release date:
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08-Dec-10
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PROCHECK
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Headers
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References
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Q9UJ71
(CLC4K_HUMAN) -
C-type lectin domain family 4 member K from Homo sapiens
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Seq:
Struc:
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328 a.a.
128 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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J Mol Biol
405:1027-1039
(2011)
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PubMed id:
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Structural basis for langerin recognition of diverse pathogen and mammalian glycans through a single binding site.
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H.Feinberg,
M.E.Taylor,
N.Razi,
R.McBride,
Y.A.Knirel,
S.A.Graham,
K.Drickamer,
W.I.Weis.
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ABSTRACT
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Links
