PDBsum entry 3p2t

Immune system

PDB id: 3p2t

Contents

Protein chain

194 a.a.

Ligands

SO4 ×3

Waters ×234

PDB id:

3p2t

Name:

Immune system

Title:

Crystal structure of leukocyte ig-like receptor lilrb4 (ilt3/lir- 5/cd85k)

Structure:

Leukocyte immunoglobulin-like receptor subfamily b member 4. Chain: a. Fragment: residues in unp 24-219. Synonym: lilrb4 (ilt3/lir-5/cd85k), leukocyte immunoglobulin-like receptor 5, lir-5, immunoglobulin-like transcript 3, ilt-3, monocyte inhibitory receptor hm18, cd85 antigen-like family member k. Engineered: yes. Mutation: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: lilrb4, ilt3, lir5. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

1.70Å R-factor: 0.187 R-free: 0.218

Authors:

Y.Chen,G.Nam,H.Cheng,J.H.Zhang,B.E.Willcox,G.F.Gao

Key ref:

H.Cheng et al. (2011). Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance. J Biol Chem, 286, 18013-18025. PubMed id: 21454581

Date:

04-Oct-10 Release date: 30-Mar-11

Protein chain

Q8NHJ6  (LIRB4_HUMAN) -  Leukocyte immunoglobulin-like receptor subfamily B member 4 from Homo sapiens

Seq: 448 a.a.

Struc: 194 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

J Biol Chem 286:18013-18025 (2011)

PubMed id: 21454581

Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): a myeloid inhibitory receptor involved in immune tolerance.

H.Cheng, F.Mohammed, G.Nam, Y.Chen, J.Qi, L.I.Garner, R.L.Allen, J.Yan, B.E.Willcox, G.F.Gao.

ABSTRACT

No abstract given.