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PDBsum entry 3obb
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Oxidoreductase
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PDB id
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3obb
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Oxidoreductase
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Title:
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Crystal structure of a possible 3-hydroxyisobutyrate dehydrogenase from pseudomonas aeruginosa pao1
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Structure:
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Probable 3-hydroxyisobutyrate dehydrogenase. Chain: a. Engineered: yes
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Source:
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Pseudomonas aeruginosa. Organism_taxid: 287. Strain: pa01. Gene: pa0743. Expressed in: escherichia coli. Expression_system_taxid: 469008.
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Resolution:
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2.20Å
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R-factor:
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0.199
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R-free:
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0.248
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Authors:
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K.Tan,A.U.Singer,E.Evdokimova,M.Kudritska,A.Savchenko,A.M.Edwards, A.F.Yakunin,A.Joachimiak,Midwest Center For Structural Genomics (Mcsg)
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Key ref:
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A.Tchigvintsev
et al.
(2012).
Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase.
J Biol Chem,
287,
1874-1883.
PubMed id:
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Date:
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06-Aug-10
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Release date:
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18-Aug-10
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Supersedes:
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PROCHECK
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Headers
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References
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Q9I5I6
(SERDH_PSEAE) -
NAD-dependent L-serine dehydrogenase from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
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Seq:
Struc:
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298 a.a.
295 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.1.1.1.387
- L-serine 3-dehydrogenase (NAD(+)).
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Reaction:
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L-serine + NAD+ = aminoacetaldehyde + CO2 + NADH
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L-serine
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NAD(+)
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=
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aminoacetaldehyde
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+
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CO2
Bound ligand (Het Group name = )
matches with 75.00% similarity
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+
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NADH
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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J Biol Chem
287:1874-1883
(2012)
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PubMed id:
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Biochemical and structural studies of uncharacterized protein PA0743 from Pseudomonas aeruginosa revealed NAD+-dependent L-serine dehydrogenase.
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A.Tchigvintsev,
A.Singer,
G.Brown,
R.Flick,
E.Evdokimova,
K.Tan,
C.F.Gonzalez,
A.Savchenko,
A.F.Yakunin.
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ABSTRACT
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Links
