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PDBsum entry 3mrb

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Immune system PDB id
3mrb

 

 

 

 

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Contents
Protein chains
275 a.a.
100 a.a.
Ligands
ASN-LEU-VAL-PRO-
MET-VAL-HIS-THR-
VAL
Waters ×387
PDB id:
3mrb
Name: Immune system
Title: Crystal structure of mhc class i hla-a2 molecule complexed with hcmv pp65-495-503 nonapeptide a7h variant
Structure: Hla class i histocompatibility antigen, a-2 alpha chain. Chain: a. Fragment: hla-a 0201 Alpha chain, unp resiude 25-300. Synonym: mhc class i antigen a 2. Engineered: yes. Mutation: yes. Beta-2-microglobulin. Chain: b. Synonym: beta-2-microglobulin form pi 5.3.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: hla, hla-a, hlaa. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: b2m, beta-2 microglubulin, cdabp0092, hdcma22p. Synthetic: yes. Human cytomegalovirus hcmv.
Resolution:
1.40Å     R-factor:   0.214     R-free:   0.244
Authors: S.Gras,J.-B.Reiser,A.Chouquet,E.Debeaupuis,K.Echasserieau,X.Saulquin, M.Bonneville,D.Housset
Key ref: S.Gras et al. Crystal structure of mhc class I hla-A2 molecule comp with short peptide. To be published, .
Date:
29-Apr-10     Release date:   25-May-11    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P04439  (1A03_HUMAN) -  HLA class I histocompatibility antigen, A alpha chain from Homo sapiens
Seq:
Struc:
365 a.a.
275 a.a.*
Protein chain
Pfam   ArchSchema ?
P61769  (B2MG_HUMAN) -  Beta-2-microglobulin from Homo sapiens
Seq:
Struc:
119 a.a.
100 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 21 residue positions (black crosses)

 

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