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PDBsum entry 3mls

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protein Protein-protein interface(s) links
Immune system PDB id
3mls

 

 

 

 

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Contents
Protein chains
219 a.a. *
226 a.a. *
20 a.a. *
Waters ×709
* Residue conservation analysis
PDB id:
3mls
Name: Immune system
Title: Crystal structure of anti-HIV-1 v3 mab 2557 fab in complex with a HIV- 1 gp120 v3 mimotope
Structure: Human monoclonal anti-HIV-1 gp120 v3 antibody 2557 fab light chain. Chain: l, m, n, o. Human monoclonal anti-HIV-1 gp120 v3 antibody 2557 fab heavy chain. Chain: h, i, j, k. Rationally designed v3 mimotope. Chain: p, q, r, s. Engineered: yes
Source: Homo sapiens. Organism_taxid: 9606. Synthetic: yes
Resolution:
2.50Å     R-factor:   0.216     R-free:   0.274
Authors: X.-P.Kong
Key ref: X.Jiang et al. (2010). Conserved structural elements in the V3 crown of HIV-1 gp120. Nat Struct Biol, 17, 955-961. PubMed id: 20622876
Date:
18-Apr-10     Release date:   14-Jul-10    
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 Headers
 References

Protein chains
No UniProt id for this chain
Struc: 219 a.a.
Protein chains
No UniProt id for this chain
Struc: 226 a.a.
Protein chains
No UniProt id for this chain
Struc: 20 a.a.
Key:    Secondary structure  CATH domain

 

 
Nat Struct Biol 17:955-961 (2010)
PubMed id: 20622876  
 
 
Conserved structural elements in the V3 crown of HIV-1 gp120.
X.Jiang, V.Burke, M.Totrov, C.Williams, T.Cardozo, M.K.Gorny, S.Zolla-Pazner, X.P.Kong.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
21209919 J.Swetnam, E.Shmelkov, S.Zolla-Pazner, and T.Cardozo (2010).
Comparative magnitude of cross-strain conservation of HIV variable loop neutralization epitopes.
  PLoS One, 5, e15994.  
20860672 Y.Voronin, and S.Phogat (2010).
HIV/AIDS: vaccines and alternate strategies for treatment and prevention.
  Ann N Y Acad Sci, 1205, E1-E9.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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