PDBsum entry 3lg0

Transferase

PDB id

3lg0

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Contents

			Protein chains

					385 a.a. *

			Waters ×400

* Residue conservation analysis

PDB id:

3lg0

Links

Name:

Transferase

Title:

Structure of plasmodium falciparum ornithine delta-aminotransferase

Structure:

Ornithine aminotransferase. Chain: a, b, c, d. Synonym: ornithine-oxo-acid aminotransferase. Engineered: yes

Source:

Plasmodium falciparum. Organism_taxid: 5836. Strain: isolate cdc / honduras. Gene: oat. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.30Å

R-factor:

0.206

R-free:

0.250

Authors:

K.Fritz-Wolf,E.Jortzik,M.Stumpf,K.Becker

Key ref:

E.Jortzik et al. (2010). Redox regulation of Plasmodium falciparum ornithine δ-aminotransferase. J Mol Biol, 402, 445-459. PubMed id: 20673832

Date:

19-Jan-10

Release date:

04-Aug-10

PROCHECK

	Headers

	References

Protein chains

Q6LFH8 (OAT_PLAF7) - Ornithine aminotransferase from Plasmodium falciparum (isolate 3D7)

Seq: Struc:					414 a.a. 385 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.2.6.1.13 - ornithine aminotransferase.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

a 2-oxocarboxylate + L-ornithine = L-glutamate 5-semialdehyde + an L-alpha-amino acid

2-oxocarboxylate	+	L-ornithine	=	L-glutamate 5-semialdehyde	+	L-alpha-amino acid

Cofactor:

Pyridoxal 5'-phosphate

Pyridoxal 5'-phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

	J Mol Biol 402:445-459 (2010)
PubMed id: 20673832

Redox regulation of Plasmodium falciparum ornithine δ-aminotransferase.
E.Jortzik, K.Fritz-Wolf, N.Sturm, M.Hipp, S.Rahlfs, K.Becker.

ABSTRACT

No abstract given.