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PDBsum entry 3gsl

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protein Protein-protein interface(s) links
Structural protein PDB id
3gsl

 

 

 

 

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Contents
Protein chains
194 a.a. *
Waters ×280
* Residue conservation analysis
PDB id:
3gsl
Name: Structural protein
Title: Crystal structure of psd-95 tandem pdz domains 1 and 2
Structure: Disks large homolog 4. Chain: a, b. Fragment: pdz domains 1 and 2: unp residues 61-249. Synonym: postsynaptic density protein 95, psd-95, synapse-associated protein 90, sap90. Engineered: yes. Other_details: psd-95/dlg4 pdz domains 1 and 2 (m61-a249)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: dlg4, dlgh4, psd-95, psd95. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Resolution:
2.05Å     R-factor:   0.221     R-free:   0.281
Authors: M.Sainlos,N.B.Olivier,B.Imperiali
Key ref: M.Sainlos et al. (2011). Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization. Nat Chem Biol, 7, 81-91. PubMed id: 21186349
Date:
27-Mar-09     Release date:   29-Sep-10    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P31016  (DLG4_RAT) -  Disks large homolog 4 from Rattus norvegicus
Seq:
Struc:
 
Seq:
Struc:
724 a.a.
194 a.a.*
Key:    PfamA domain  Secondary structure  CATH domain
* PDB and UniProt seqs differ at 5 residue positions (black crosses)

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
Nat Chem Biol 7:81-91 (2011)
PubMed id: 21186349  
 
 
Biomimetic divalent ligands for the acute disruption of synaptic AMPAR stabilization.
M.Sainlos, C.Tigaret, C.Poujol, N.B.Olivier, L.Bard, C.Breillat, K.Thiolon, D.Choquet, B.Imperiali.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
21521608 A.C.Jackson, and R.A.Nicoll (2011).
The expanding social network of ionotropic glutamate receptors: TARPs and other transmembrane auxiliary subunits.
  Neuron, 70, 178-199.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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