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PDBsum entry 3gos
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Contents |
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* Residue conservation analysis
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PDB id:
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Transferase
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Title:
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The crystal structure of 2,3,4,5-tetrahydropyridine-2-carboxylate n- succinyltransferase from yersinia pestis co92
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Structure:
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2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n- succinyltransferase. Chain: a, b, c. Synonym: tetrahydrodipicolinate n-succinyltransferase, thp succinyltransferase, tetrahydropicolinate succinylase. Engineered: yes
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Source:
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Yersinia pestis. Organism_taxid: 632. Strain: co92. Gene: dapd, gi: 16121341, y3140, ypo1041, yp_2810. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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1.80Å
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R-factor:
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0.230
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R-free:
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0.272
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Authors:
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R.Zhang,N.Maltseva,K.Kwon,W.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)
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Key ref:
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R.Zhang
et al.
The crystal structure of 2,3,4,5-Tetrahydropyridine-2-Carboxylate n-Succinyltransferase from yersinia pestis co92.
To be published,
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Date:
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19-Mar-09
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Release date:
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12-May-09
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PROCHECK
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Headers
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References
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Q8ZH69
(DAPD_YERPE) -
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase from Yersinia pestis
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Seq:
Struc:
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274 a.a.
270 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.3.1.117
- 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase.
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Pathway:
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Lysine biosynthesis (later stages)
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Reaction:
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(S)-2,3,4,5-tetrahydrodipicolinate + succinyl-CoA + H2O = (S)-2- succinylamino-6-oxoheptanedioate + CoA
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(S)-2,3,4,5-tetrahydrodipicolinate
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+
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succinyl-CoA
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+
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H2O
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=
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(S)-2- succinylamino-6-oxoheptanedioate
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+
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CoA
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
