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PDBsum entry 3f0n
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Lyase
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Title:
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Mus musculus mevalonate pyrophosphate decarboxylase
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Structure:
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Mevalonate pyrophosphate decarboxylase. Chain: a, b. Synonym: diphosphomevalonate decarboxylase. Engineered: yes
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Source:
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Mus musculus. Mouse. Organism_taxid: 10090. Gene: mvd. Expressed in: escherichia coli. Expression_system_taxid: 562.
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Resolution:
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1.90Å
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R-factor:
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0.184
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R-free:
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0.221
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Authors:
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J.R.Walker,T.Davis,A.Vesterberg,Y.Li,C.Bountra,J.Weigelt, C.H.Arrowsmith,A.M.Edwards,A.Bochkarev,S.Dhe-Paganon,Structural Genomics Consortium (Sgc)
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Key ref:
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J.R.Walker
et al.
Structure of mus musculus mevalonate pyrophosphate decarboxylase.
To be published,
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Date:
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25-Oct-08
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Release date:
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25-Nov-08
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PROCHECK
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Headers
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References
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Q99JF5
(MVD1_MOUSE) -
Diphosphomevalonate decarboxylase from Mus musculus
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Seq:
Struc:
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401 a.a.
387 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 8 residue positions (black
crosses)
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Enzyme class:
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E.C.4.1.1.33
- diphosphomevalonate decarboxylase.
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Pathway:
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Terpenoid biosynthesis
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Reaction:
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(R)-5-diphosphomevalonate + ATP = isopentenyl diphosphate + ADP + phosphate + CO2
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(R)-5-diphosphomevalonate
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+
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ATP
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=
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isopentenyl diphosphate
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+
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ADP
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+
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phosphate
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+
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CO2
Bound ligand (Het Group name = )
corresponds exactly
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
