PDBsum entry 3eom

Oxidoreductase

PDB id: 3eom

Contents

Protein chains

387 a.a. *

Waters ×167

* Residue conservation analysis

PDB id:

3eom

Name:

Oxidoreductase

Title:

2.4 a crystal structure of native glutaryl-coa dehydrogenase from burkholderia pseudomallei

Structure:

Glutaryl-coa dehydrogenase. Chain: a, b, c, d. Engineered: yes

Source:

Burkholderia pseudomallei. Organism_taxid: 320372. Strain: 1710b. Gene: burps1710b_2458, burps1710b_3237, msrb. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.40Å R-factor: 0.213 R-free: 0.264

Authors:

Seattle Structural Genomics Center For Infectious Disease (Ssgcid)

Key ref:

D.W.Begley et al. (2011). Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening. Acta Crystallogr Sect F Struct Biol Cryst Commun, 67, 1060-1069. PubMed id: 21904051

Date:

28-Sep-08 Release date: 21-Oct-08

Protein chains

Q3JP94  (Q3JP94_BURP1) -  glutaryl-CoA dehydrogenase (ETF) from Burkholderia pseudomallei (strain 1710b)

Seq: 395 a.a.

Struc: 387 a.a.

Enzyme reactions

• Enzyme class: E.C.1.3.8.6 - glutaryl-CoA dehydrogenase (ETF).
• Reaction: glutaryl-CoA + oxidized [electron-transfer flavoprotein] + 2 H⁺ = (2E)- butenoyl-CoA + reduced [electron-transfer flavoprotein] + CO2
• Cofactor: FAD

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

Acta Crystallogr Sect F Struct Biol Cryst Commun 67:1060-1069 (2011)

PubMed id: 21904051

Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening.

D.W.Begley, D.R.Davies, R.C.Hartley, S.N.Hewitt, A.L.Rychel, P.J.Myler, W.C.Van Voorhis, B.L.Staker, L.J.Stewart.

ABSTRACT

No abstract given.