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PDBsum entry 3cqe
Go to PDB code: 
protein ligands metals links
Transferase PDB id
3cqe

 

 

 

 

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JSmol PyMol  
Contents
Protein chain
258 a.a. *
Ligands
P91
GOL
Metals
_CL
Waters ×49
* Residue conservation analysis
PDB id:
3cqe
Name: Transferase
Title: Wee1 kinase complex with inhibitor pd074291
Structure: Wee1-like protein kinase. Chain: a. Fragment: kinase domain. Synonym: wee1a kinase, wee1hu. Engineered: yes
Source: Homo sapiens. Organism_taxid: 9606. Gene: wee1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Resolution:
2.50Å     R-factor:   0.212     R-free:   0.268
Authors: C.J.Squire,E.N.Baker
Key ref: C.J.Squire et al. Structural determinants of wee1 inhibitor selectivity. To be published, .
Date:
02-Apr-08     Release date:   24-Feb-09    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chain
Pfam   ArchSchema ?
P30291  (WEE1_HUMAN) -  Wee1-like protein kinase from Homo sapiens
Seq:
Struc: 		 
Seq:
Struc: 		646 a.a.
258 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.2.7.10.2  - non-specific protein-tyrosine kinase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]
      Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H+
L-tyrosyl-[protein]
 + ATP
 = O-phospho-L-tyrosyl-[protein]
 + ADP
 + H(+)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

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