PDBsum entry 3asb

Transferase

PDB id: 3asb

Contents

Protein chain

364 a.a.

Waters ×39

PDB id:

3asb

Name:

Transferase

Title:

Crystal structure of plp-bound ll-diaminopimelate aminotransferase from chlamydia trachomatis

Structure:

Ll-diaminopimelate aminotransferase. Chain: a. Synonym: ll-dap-aminotransferase. Engineered: yes

Source:

Chlamydia trachomatis. Organism_taxid: 813. Gene: dapl, aspc, ct_390. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

2.70Å R-factor: 0.225 R-free: 0.287

Authors:

N.Watanabe,M.N.James

Key ref:

N.Watanabe et al. (2011). The structure of LL-diaminopimelate aminotransferase from Chlamydia trachomatis: implications for its broad substrate specificity. J Mol Biol, 411, 649-660. PubMed id: 21722650

Date:

10-Dec-10 Release date: 31-Aug-11

Protein chain

O84395  (DAPAT_CHLTR) -  LL-diaminopimelate aminotransferase from Chlamydia trachomatis serovar D (strain ATCC VR-885 / DSM 19411 / UW-3/Cx)

Seq: 394 a.a.

Struc: 364 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.2.6.1.83 - LL-diaminopimelate aminotransferase.
• Reaction: (2S,6S)-2,6-diaminopimelate + 2-oxoglutarate = (S)-2,3,4,5- tetrahydrodipicolinate + L-glutamate + H2O + H⁺
• Cofactor: Pyridoxal 5'-phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site

reference

J Mol Biol 411:649-660 (2011)

PubMed id: 21722650

The structure of LL-diaminopimelate aminotransferase from Chlamydia trachomatis: implications for its broad substrate specificity.

N.Watanabe, M.D.Clay, M.J.van Belkum, C.Fan, J.C.Vederas, M.N.James.

ABSTRACT

No abstract given.