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PDBsum entry 2yzd

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protein ligands Protein-protein interface(s) links
Oxidoreductase PDB id
2yzd

 

 

 

 

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Contents
Protein chains
(+ 2 more) 287 a.a. *
Ligands
AZA ×8
Waters ×1160
* Residue conservation analysis
PDB id:
2yzd
Name: Oxidoreductase
Title: Crystal structure of uricase from arthrobacter globiformis in complex with 8-azaxanthin (inhibitor)
Structure: Uricase. Chain: a, b, c, d, e, f, g, h. Ec: 1.7.3.3
Source: Arthrobacter globiformis
Resolution:
2.24Å     R-factor:   0.189     R-free:   0.239
Authors: E.C.M.Juan,M.T.Hossain,M.M.Hoque,K.Suzuki,T.Sekiguchi,A.Takenaka
Key ref: E.C.M.Juan et al. Trapping of the uric acid substrate in the crystal structure of urate oxidase from arthrobacter globiformis. To be published, . PubMed id: 18645230
Date:
05-May-07     Release date:   06-May-08    
PROCHECK
Go to PROCHECK summary
 Headers
 References

Protein chains
D0VWQ1  (URIC_ARTGO) -  Uricase from Arthrobacter globiformis
Seq:
Struc:
302 a.a.
287 a.a.
Key:    Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.1.7.3.3  - factor independent urate hydroxylase.
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

      Pathway:
AMP Catabolism
      Reaction: urate + O2 + H2O = 5-hydroxyisourate + H2O2
urate
Bound ligand (Het Group name = AZA)
matches with 76.92% similarity
+ O2
+ H2O
= 5-hydroxyisourate
+ H2O2
      Cofactor: Copper
Molecule diagrams generated from .mol files obtained from the KEGG ftp site

 

 

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