PDBsum entry 2yw3

Lyase

PDB id: 2yw3

Contents

Protein chains

(+ 0 more) 195 a.a. *

Ligands

PO4 ×17

Waters ×1023

* Residue conservation analysis

PDB id:

2yw3

Name:

Lyase

Title:

Crystal structure analysis of the 4-hydroxy-2-oxoglutarate aldolase/2- deydro-3-deoxyphosphogluconate aldolase from tthb1

Structure:

4-hydroxy-2-oxoglutarate aldolase/2-deydro-3- deoxyphosphogluconate aldolase. Chain: a, b, c, d, e, f. Engineered: yes

Source:

Thermus thermophilus. Organism_taxid: 300852. Strain: hb8. Expressed in: escherichia coli. Expression_system_taxid: 562

Resolution:

1.67Å R-factor: 0.185 R-free: 0.214

Authors:

Y.Kawano,K.Hashimoto,N.Kamiya,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

Y.Kawano et al. Crystal structure analysis of the 4-Hydroxy-2-Oxoglutarate aldolase/2-Deydro-3-Deoxyphosphogluconate aldolase from tthb1. To be published, .

Date:

19-Apr-07 Release date: 23-Oct-07

Protein chains

Q53W90  (Q53W90_THET8) -  2-dehydro-3-deoxy-phosphogluconate aldolase from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)

Seq: 207 a.a.

Struc: 195 a.a.

Enzyme reactions

• Enzyme class: E.C.4.1.2.14 - 2-dehydro-3-deoxy-phosphogluconate aldolase.
• Reaction: 2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate + pyruvate

2-dehydro-3-deoxy-6-phospho-D-gluconate = D-glyceraldehyde 3-phosphate (Bound ligand (Het Group name = PO4) matches with 50.00% similarity) + pyruvate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site