PDBsum entry 2ys2

Transferase

PDB id: 2ys2

Contents

Protein chain

50 a.a. *

Metals

_ZN

* Residue conservation analysis

PDB id:

2ys2

Name:

Transferase

Title:

Solution structure of the btk motif of human cytoplasmic tyrosine- protein kinase bmx

Structure:

Cytoplasmic tyrosine-protein kinase bmx. Chain: a. Fragment: btk. Synonym: bone marrow tyrosine kinase gene in chromosome x protein, epithelial and endothelial tyrosine kinase, etk, ntk38. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: bmx. Other_details: cell-free protein synthesis

NMR struc:

20 models

Authors:

H.Abe,N.Tochio,T.Tomizawa,S.Koshiba,M.Yoneyama,M.Inoue,T.Kigawa, S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

H.Abe et al. Solution structure of the btk motif of human cytoplasmic tyrosine-Protein kinase bmx. To be published, .

Date:

03-Apr-07 Release date: 09-Oct-07

Protein chain

P51813  (BMX_HUMAN) -  Cytoplasmic tyrosine-protein kinase BMX from Homo sapiens

Seq: 675 a.a.

Struc: 50 a.a.*

* PDB and UniProt seqs differ at 12 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.10.2 - non-specific protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site