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PDBsum entry 2y9c
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protein dna_rna Protein-protein interface(s) links
Splicing/RNA PDB id
2y9c

 

 

 

 

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Contents
Protein chains
90 a.a.
97 a.a.
105 a.a.
89 a.a.
84 a.a.
82 a.a.
73 a.a.
75 a.a.
92 a.a.
78 a.a.
DNA/RNA
Obsolete entry
PDB id:
2y9c
Name: Splicing/RNA
Title: Structure of the spliceosomal u4 snrnp core domain
Structure: Small nuclear ribonucleoprotein-associated proteins b and b'. Chain: a, h, o. Fragment: residues 1-95. Synonym: sm protein b/b', snrnp-b, sm-b/b', smb/b'. Engineered: yes. Small nuclear ribonucleoprotein sm d1. Chain: b, i, p. Synonym: sm-d autoantigen, snrnp core protein d1, sm-d1.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: snrpb. Expressed in: escherichia coli. Expression_system_taxid: 83333. Expression_system_variant: sg13009(prep4). Other_details: coexpressed with sm-d3. Gene: snrpd1.
Resolution:
3.60Å     R-factor:   0.278     R-free:   0.321
Authors: A.K.W.Leung,K.Nagai,J.Li
Key ref: A.K.Leung et al. (2011). Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis. Nature, 473, 536-539. PubMed id: 21516107
Date:
13-Feb-11     Release date:   11-May-11    
PROCHECK
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 Headers
 References

Protein chains
Pfam   ArchSchema ?
P14678  (RSMB_HUMAN) -  Small nuclear ribonucleoprotein-associated proteins B and B' from Homo sapiens
Seq:
Struc: 		240 a.a.
90 a.a.
Protein chains
Pfam   ArchSchema ?
P62314  (SMD1_HUMAN) -  Small nuclear ribonucleoprotein Sm D1 from Homo sapiens
Seq:
Struc: 		119 a.a.
97 a.a.
Protein chains
Pfam   ArchSchema ?
P62316  (SMD2_HUMAN) -  Small nuclear ribonucleoprotein Sm D2 from Homo sapiens
Seq:
Struc: 		118 a.a.
105 a.a.
Protein chains
Pfam   ArchSchema ?
P62318  (SMD3_HUMAN) -  Small nuclear ribonucleoprotein Sm D3 from Homo sapiens
Seq:
Struc: 		126 a.a.
89 a.a.
Protein chain
Pfam   ArchSchema ?
P62304  (RUXE_HUMAN) -  Small nuclear ribonucleoprotein E from Homo sapiens
Seq:
Struc: 		92 a.a.
84 a.a.
Protein chains
Pfam   ArchSchema ?
P62306  (RUXF_HUMAN) -  Small nuclear ribonucleoprotein F from Homo sapiens
Seq:
Struc: 		86 a.a.
82 a.a.
Protein chains
Pfam   ArchSchema ?
P62308  (RUXG_HUMAN) -  Small nuclear ribonucleoprotein G from Homo sapiens
Seq:
Struc: 		76 a.a.
73 a.a.
Protein chain
Pfam   ArchSchema ?
P62304  (RUXE_HUMAN) -  Small nuclear ribonucleoprotein E from Homo sapiens
Seq:
Struc: 		92 a.a.
75 a.a.
Protein chain
Pfam   ArchSchema ?
P62316  (SMD2_HUMAN) -  Small nuclear ribonucleoprotein Sm D2 from Homo sapiens
Seq:
Struc: 		118 a.a.
92 a.a.
Protein chain
Pfam   ArchSchema ?
P62304  (RUXE_HUMAN) -  Small nuclear ribonucleoprotein E from Homo sapiens
Seq:
Struc: 		92 a.a.
78 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

DNA/RNA chains
  G-C-C-G-U-G-A-C-G-A-C-U-G-A-A-A-A-G-U-C-G-G-C-A-U-U-G-G-C-A-A-U-U-U-U-U-G-A-C- 68 bases
  G-C-C-G-U-G-A-C-G-A-C-U-G-A-A-A-A-G-U-C-G-G-C-A-U-U-G-G-C-A-A-U-U-U-U-U-G-A-C- 68 bases
  G-C-C-G-U-G-A-C-G-A-C-U-G-A-A-A-A-G-U-C-G-G-C-A-U-U-G-G-C-A-A-U-U-U-U-U-G-A-C- 68 bases

 

 
Nature 473:536-539 (2011)
PubMed id: 21516107  
 
 
Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis.
A.K.Leung, K.Nagai, J.Li.
 
  ABSTRACT  
 
No abstract given.

 

 

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