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PDBsum entry 2xwc
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DNA binding protein
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PDB id
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2xwc
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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DNA binding protein
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Title:
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Crystal structure of the DNA binding domain of human tp73 refined at 1.8 a resolution
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Structure:
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Tumour protein p73. Chain: a. Fragment: DNA-binding domain, residues 112-311. Synonym: p53-like transcription factor, p53-related protein. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: r3-prare2.
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Resolution:
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1.82Å
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R-factor:
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0.191
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R-free:
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0.228
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Authors:
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P.Canning,Y.Zhang,M.Vollmar,T.Krojer,E.Ugochukwu,J.R.C.Muniz,F.Von Delft,J.Weigelt,C.H.Arrowsmith,A.M.Edwards,C.Bountra,A.N.Bullock
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Key ref:
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P.Canning
et al.
(2012).
Structural basis for ASPP2 recognition by the tumor suppressor p73.
J Mol Biol,
423,
515-527.
PubMed id:
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Date:
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03-Nov-10
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Release date:
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17-Nov-10
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Supersedes:
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PROCHECK
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Headers
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References
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O15350
(P73_HUMAN) -
Tumor protein p73 from Homo sapiens
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Seq:
Struc:
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636 a.a.
204 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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*
PDB and UniProt seqs differ
at 6 residue positions (black
crosses)
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J Mol Biol
423:515-527
(2012)
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PubMed id:
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Structural basis for ASPP2 recognition by the tumor suppressor p73.
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P.Canning,
F.von Delft,
A.N.Bullock.
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ABSTRACT
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Links
