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PDBsum entry 2w4l
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Contents |
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160 a.a.
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142 a.a.
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150 a.a.
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* Residue conservation analysis
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PDB id:
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Hydrolase
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Title:
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Human dcmp deaminase
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Structure:
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Deoxycytidylate deaminase. Chain: a, b, c, d, e, f. Fragment: 5-173. Synonym: dcmp deaminse. Engineered: yes. Other_details: construct has c-terminal histag
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: mgc
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Resolution:
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2.10Å
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R-factor:
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0.202
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R-free:
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0.243
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Authors:
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M.I.Siponen,M.Moche,C.H.Arrowsmith,H.Berglund,C.Bountra,R.Collins, L.G.Dahlgren,A.M.Edwards,S.Flodin,A.Flores,S.Graslund,M.Hammarstrom, A.Johansson,I.Johansson,T.Karlberg,T.Kotenyova,L.Lehtio,M.E.Nilsson, T.Nyman,C.Persson,J.Sagemark,H.Schuler,A.G.Thorsell,L.Tresaugues, S.Van Den Berg,J.Weigelt,M.Welin,M.Wikstrom,M.Wisniewska,P.Nordlund
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Key ref:
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M.I.Siponen
et al.
The crystal structure of human dcmp deaminase.
To be published,
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Date:
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28-Nov-08
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Release date:
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13-Jan-09
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PROCHECK
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Headers
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References
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P32321
(DCTD_HUMAN) -
Deoxycytidylate deaminase from Homo sapiens
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Seq:
Struc:
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178 a.a.
160 a.a.
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Enzyme class:
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Chains A, B, C, D, E, F:
E.C.3.5.4.12
- dCMP deaminase.
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Reaction:
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dCMP + H2O + H+ = dUMP + NH4+
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dCMP
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+
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H2O
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+
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H(+)
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=
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dUMP
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+
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NH4(+)
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
