PDBsum entry 2v8b

Hydrolase

PDB id: 2v8b

Contents

Protein chain

279 a.a. *

Ligands

SE4

Metals

_CA

Waters ×538

* Residue conservation analysis

PDB id:

2v8b

Name:

Hydrolase

Title:

Sad structure solution of proteinase k grown in selenate solution

Structure:

Proteinase k. Chain: a. Fragment: residues 106-384. Synonym: tritirachium alkaline proteinase, endopeptidase k. Ec: 3.4.21.64

Source:

Engyodontium album. Organism_taxid: 37998

Resolution:

0.94Å R-factor: 0.091 R-free: 0.103

Authors:

J.Jakoncic,V.Stojanoff

Key ref:

J.Jakoncic and v.stojanoff Selenate substitution: application in protein crystallography. To be published, .

Date:

06-Aug-07 Release date: 26-Aug-08

Protein chain

P06873  (PRTK_PARAQ) -  Proteinase K from Parengyodontium album

Seq: 384 a.a.

Struc: 279 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.3.4.21.64 - peptidase K.
• Reaction: Hydrolysis of keratin and of other proteins, with subtilisin-like specificity. Hydrolyzes peptides amides.