PDBsum entry 2r6h

Oxidoreductase

PDB id: 2r6h

Contents

Protein chains

285 a.a. *

Ligands

SO4 ×11

FAD ×4

Waters ×254

* Residue conservation analysis

PDB id:

2r6h

Name:

Oxidoreductase

Title:

Crystal structure of the domain comprising the NAD binding and the fad binding regions of the nadh:ubiquinone oxidoreductase, na translocating, f subunit from porphyromonas gingivalis

Structure:

Nadh:ubiquinone oxidoreductase, na translocating, f subunit. Chain: a, b, c, d. Fragment: the NAD and fad binding region: residues 126-412. Engineered: yes

Source:

Porphyromonas gingivalis. Organism_taxid: 242619. Strain: w83. Atcc: baa-308. Gene: nqrf, pg_2177. Expressed in: escherichia coli. Expression_system_taxid: 562.

Resolution:

2.95Å R-factor: 0.221 R-free: 0.271

Authors:

Y.Kim,R.Mulligan,S.Moy,A.Joachimiak,Midwest Center For Structural Genomics (Mcsg)

Key ref:

Y.Kim et al. Crystal structure of the domain comprising the regions binding NAD and FAD from the nadh:ubiquinone oxidoreductase, Na translocating, F subunit from porphyromonas gingivalis.. To be published, .

Date:

05-Sep-07 Release date: 11-Sep-07

Protein chains

Q7MT22  (Q7MT22_PORGI) -  Na(+)-translocating NADH-quinone reductase subunit F from Porphyromonas gingivalis (strain ATCC BAA-308 / W83)

Seq: 412 a.a.

Struc: 285 a.a.

Enzyme reactions

• Enzyme class: E.C.7.2.1.1 - NADH:ubiquinone reductase (Na(+)-transporting).
• Reaction: a ubiquinone + n Na⁺(in) + NADH + H⁺ = a ubiquinol + n Na⁺(out) + NAD(+)
• Cofactor: FAD; FMN; Iron-sulfur; Riboflavin

FAD (Bound ligand (Het Group name = FAD) corresponds exactly) FMN Iron-sulfur Riboflavin

Molecule diagrams generated from .mol files obtained from the KEGG ftp site