PDBsum entry 2pyc

Hydrolase

PDB id: 2pyc

Contents

Protein chain

121 a.a. *

Ligands

ACT ×3

SO4 ×2

CCN

Waters ×281

* Residue conservation analysis

PDB id:

2pyc

Name:

Hydrolase

Title:

Crystal structure of a monomeric phospholipase a2 from russell's viper at 1.5a resolution

Structure:

Phospholipase a2 vrv-pl-viiia. Chain: a. Synonym: phosphatidylcholine 2-acylhydrolase, dpla2. Ec: 3.1.1.4

Source:

Daboia russellii pulchella. Organism_taxid: 97228. Strain: pulchella

Resolution:

1.50Å R-factor: 0.182 R-free: 0.216

Authors:

S.Kumar,N.Singh,S.Sharma,P.Kaur,C.Betzel,T.P.Singh

Key ref:

S.Kumar et al. Crystal structure of a monomeric phospholipase a2 from russell'S viper at 1.5a resolution. To be published, .

Date:

16-May-07 Release date: 29-May-07

Protein chain

P59071  (PA2B8_DABRR) -  Basic phospholipase A2 VRV-PL-VIIIa from Daboia russelii

Seq: 121 a.a.

Struc: 121 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.1.4 - phospholipase A2.
• Reaction: a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3- phosphocholine + a fatty acid + H⁺

1,2-diacyl-sn-glycero-3-phosphocholine + H2O = 1-acyl-sn-glycero-3- phosphocholine + fatty acid (Bound ligand (Het Group name = ACT) matches with 60.00% similarity) + H(+)

• Cofactor: Ca(2+)

Molecule diagrams generated from .mol files obtained from the KEGG ftp site