 |
PDBsum entry 2oyf
|
|
|
|
 |
Contents |
 |
|
|
|
|
|
|
|
|
|
|
|
* Residue conservation analysis
|
|
|
|
|
PDB id:
|
 |
|
 |
| Name: |
 |
Hydrolase
|
 |
|
Title:
|
 |
Crystal structure of the complex of phospholipase a2 with indole acetic acid at 1.2 a resolution
|
|
Structure:
|
 |
Phospholipase a2 vrv-pl-viiia. Chain: a. Synonym: phospholipase a2, phosphatidylcholine 2-acylhydrolase, dpla2. Ec: 3.1.1.4
|
|
Source:
|
 |
Daboia russellii pulchella. Organism_taxid: 97228. Strain: pulchella. Secretion: venom
|
|
Resolution:
|
 |
|
1.20Å
|
R-factor:
|
0.189
|
R-free:
|
0.208
|
|
|
Authors:
|
 |
S.Kumar,G.Hariprasad,N.Singh,S.Sharma,P.Kaur,M.Perbandt,C.Betzel, T.P.Singh
|
|
Key ref:
|
 |
S.Kumar
et al.
Crystal structure of the complex of phospholipase a2 with indole acetic acid at 1.2 a resolution.
To be published,
.
|
 |
|
Date:
|
 |
|
22-Feb-07
|
Release date:
|
20-Mar-07
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
Headers
|
 |
|
|
References
|
|
|
|
|
|
|
P59071
(PA2B8_DABRR) -
Basic phospholipase A2 VRV-PL-VIIIa from Daboia russelii
|
|
|
|
Seq: Struc:
|
 |
 |
 |
121 a.a.
121 a.a.
|
|
|
|
|
|
|
|
|
 |
 |
|
|
Key: |
 |
PfamA domain |
 |
 |
 |
Secondary structure |
 |
 |
CATH domain |
 |
|
|
|
|
 |
|
|
 |
 |
 |
 |
Enzyme class:
|
 |
E.C.3.1.1.4
- phospholipase A2.
|
|
 |
 |
 |
 |
 |
Reaction:
|
 |
a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3- phosphocholine + a fatty acid + H+
|
 |
 |
 |
 |
 |
1,2-diacyl-sn-glycero-3-phosphocholine
|
+
|
H2O
|
=
|
1-acyl-sn-glycero-3- phosphocholine
|
+
|
fatty acid
Bound ligand (Het Group name = )
matches with 60.00% similarity
|
+
|
H(+)
|
|
 |
 |
 |
 |
 |
 |
 |
 |
Cofactor:
|
 |
Ca(2+)
|
 |
 |
 |
 |
 |
 |
 |
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
 |
');
}
}
 |