 |
PDBsum entry 2oxc
|
|
|
|
|
 |
Contents |
 |
|
|
|
|
|
|
|
|
|
|
|
|
* Residue conservation analysis
|
|
|
|
|
|
PDB id:
|
|
|
|
| Name: |
|
Hydrolase
|
|
|
Title:
|
|
Human dead-box RNA helicase ddx20, dead domain in complex with adp
|
|
Structure:
|
|
Probable atp-dependent RNA helicase ddx20. Chain: a, b. Fragment: dead domain. Synonym: dead box protein 20, dead box protein dp 103, component of gems 3, gemin-3. Engineered: yes
|
|
Source:
|
|
Homo sapiens. Human. Organism_taxid: 9606. Gene: ddx20, dp103, gemin3. Expressed in: escherichia coli. Expression_system_taxid: 562.
|
|
Resolution:
|
|
|
1.30Å
|
R-factor:
|
0.154
|
R-free:
|
0.175
|
|
|
Authors:
|
|
T.Karlberg,D.Ogg,C.H.Arrowsmith,H.Berglund,R.D.Busam,R.Collins, L.G.Dahlgren,A.Edwards,S.Flodin,A.Flores,S.Graslund,B.M.Hallberg, M.Hammarstrom,M.Hogbom,I.Johansson,T.Kotenyova,L.Lehtio,M.Moche, P.Nordlund,T.Nyman,C.Persson,J.Sagemark,P.Stenmark,M.Sundstrom, A.G.Thorsell,S.Van Den Berg,J.Weigelt,L.Holmberg-Schiavone, Structural Genomics Consortium (Sgc)
|
|
Key ref:
|
|
T.Karlberg
et al.
Human dead-Box RNA helicase ddx20.
To be published,
.
|
|
|
Date:
|
|
|
20-Feb-07
|
Release date:
|
27-Feb-07
|
|
|
|
|
|
|
PROCHECK
|
|
|
|
|
|
Headers
|
|
|
|
References
|
|
|
|
|
|
|
|
Q9UHI6
(DDX20_HUMAN) -
Probable ATP-dependent RNA helicase DDX20 from Homo sapiens
|
|
|
|
Seq:
Struc:
|
|
|
|
824 a.a.
205 a.a.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Key: |
 |
PfamA domain |
|
|
 |
Secondary structure |
|
 |
CATH domain |
|
|
|
|
|
|
|
|
|
|
|
|
|
Enzyme class 1:
|
|
E.C.3.6.1.15
- nucleoside-triphosphate phosphatase.
|
|
|
|
|
|
|
Reaction:
|
|
a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'-diphosphate + phosphate + H+
|
|
|
|
|
|
ribonucleoside 5'-triphosphate
|
+
|
H2O
|
=
|
ribonucleoside 5'-diphosphate
|
+
|
phosphate
|
+
|
H(+)
|
|
|
|
|
|
|
|
|
|
Enzyme class 2:
|
|
E.C.3.6.4.13
- Rna helicase.
|
|
|
|
|
|
|
Reaction:
|
|
ATP + H2O = ADP + phosphate + H+
|
|
|
|
|
|
ATP
|
+
|
H2O
|
=
|
ADP
Bound ligand (Het Group name = )
corresponds exactly
|
+
|
phosphate
|
+
|
H(+)
|
|
|
|
|
|
|
|
|
|
|
|
|
Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
|
|
|
|
Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
|
|
|
|
Links
