PDBsum entry 2o4x

Hydrolase

PDB id: 2o4x

Contents

Protein chains

217 a.a. *

87 a.a. *

Waters ×156

* Residue conservation analysis

PDB id:

2o4x

Name:

Hydrolase

Title:

Crystal structure of human p100 tudor domain

Structure:

Staphylococcal nuclease domain-containing protein 1. Chain: a. Fragment: residues 654-870. Synonym: p100 co-activator, 100 kda coactivator, ebna2 coactivator p100. Engineered: yes. Staphylococcal nuclease domain-containing protein 1. Chain: b. Fragment: residues 680-795.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.

Resolution:

2.00Å R-factor: 0.234 R-free: 0.249

Authors:

N.Shaw,M.Zhao,C.Cheng,H.Xu,J.Yang,O.Silvennoinen,Z.Rao,B.C.Wang, Z.J.Liu

Key ref:

N.Shaw et al. Crystal structure of human p100 tudor domain. To be published, .

Date:

05-Dec-06 Release date: 13-Feb-07

Protein chain

Q7KZF4  (SND1_HUMAN) -  Staphylococcal nuclease domain-containing protein 1 from Homo sapiens

Seq: 910 a.a.

Struc: 217 a.a.*

Protein chain

Q7KZF4  (SND1_HUMAN) -  Staphylococcal nuclease domain-containing protein 1 from Homo sapiens

Seq: 910 a.a.

Struc: 87 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chains A, B: E.C.3.1.31.1 - micrococcal nuclease.
• Reaction: Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.