PDBsum entry 2mpc

Signaling protein

PDB id: 2mpc

Contents

Protein chain

90 a.a.

PDB id:

2mpc

Name:

Signaling protein

Title:

Solution structure of the pyrin domain of human pyrin

Structure:

Pyrin. Chain: a. Fragment: dapin domain (pyd), residues 1-92. Synonym: marenostrin. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: mefv, mef. Expressed in: escherichia coli. Expression_system_taxid: 562.

NMR struc:

10 models

Authors:

S.L.Soh,S.J.Smith,J.M.Hill

Key ref:

P.R.Vajjhala et al. Identification of multifaceted binding modes for pyri asc pyrin domains gives insights into pyrin inflammas assembly. To be published, . PubMed id: 25006247

Date:

15-May-14 Release date: 16-Jul-14

Protein chain

O15553  (MEFV_HUMAN) -  Pyrin from Homo sapiens

Seq: 781 a.a.

Struc: 90 a.a.*

* PDB and UniProt seqs differ at 1 residue position (black cross)

Enzyme reactions

• Enzyme class: E.C.?