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PDBsum entry 2mg0
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PDB id:
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Hydrolase
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Title:
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Pap262-270 in sds micelles
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Structure:
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Peptide from prostatic acid phosphatase. Chain: a. Synonym: pap, 5'-nucleotidase, 5'-nt, ecto-5'-nucleotidase, thiamine monophosphatase, tmpase, papf39. Engineered: yes
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Source:
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Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
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NMR struc:
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20 models
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Authors:
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D.Blokhin,V.Vklochkov,A.Filippov,O.Antzutkin
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Key ref:
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D.Blokhin
Pap262-270 in sds micelles.
To be published,
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Date:
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24-Oct-13
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Release date:
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29-Oct-14
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PROCHECK
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Headers
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References
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P15309
(PPAP_HUMAN) -
Prostatic acid phosphatase from Homo sapiens
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Seq:
Struc:
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386 a.a.
10 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 1 residue position (black
cross)
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Enzyme class 1:
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E.C.3.1.3.2
- acid phosphatase.
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Reaction:
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a phosphate monoester + H2O = an alcohol + phosphate
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phosphate monoester
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+
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H2O
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=
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alcohol
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+
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phosphate
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Enzyme class 2:
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E.C.3.1.3.48
- protein-tyrosine-phosphatase.
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Reaction:
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O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate
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O-phospho-L-tyrosyl-[protein]
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+
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H2O
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=
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L-tyrosyl-[protein]
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+
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phosphate
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Enzyme class 3:
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E.C.3.1.3.5
- 5'-nucleotidase.
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Reaction:
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a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate
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ribonucleoside 5'-phosphate
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+
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H2O
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=
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ribonucleoside
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+
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phosphate
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Note, where more than one E.C. class is given (as above), each may
correspond to a different protein domain or, in the case of polyprotein
precursors, to a different mature protein.
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Molecule diagrams generated from .mol files obtained from the
KEGG ftp site
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Links
