PDBsum entry 2m7h

Hydrolase

PDB id: 2m7h

Contents

Protein chain

71 a.a.

PDB id:

2m7h

Name:

Hydrolase

Title:

ThE C-terminal region of disintegrin modulate its 3d conformation and cooperate with rgd loop in regulating integrin alpha-iib beta-3 recognition

Structure:

Zinc metalloproteinase/disintegrin. Chain: a. Fragment: unp residues 408-478. Synonym: snake venom metalloproteinase rhodostoxin, svmp, hemorrhagic protein, disintegrin rhodostomin, rho, disintegrin kistrin, platelet aggregation activation inhibitor. Engineered: yes. Mutation: yes

Source:

Calloselasma rhodostoma. Malayan pit viper. Organism_taxid: 8717. Gene: rhod. Expressed in: komagataella pastoris. Expression_system_taxid: 4922.

NMR struc:

20 models

Authors:

W.Chuang,Y.Chang

Key ref:

W.Chuang et al. The c-Terminal region of disintegrin modulate its 3d conformation and cooperate with rgd loop in regulatin recognitions of integrins. To be published, .

Date:

22-Apr-13 Release date: 22-May-13

Protein chain

P30403  (VM2RH_CALRH) -  Zinc metalloproteinase/disintegrin from Calloselasma rhodostoma

Seq: 478 a.a.

Struc: 71 a.a.*

* PDB and UniProt seqs differ at 8 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.3.4.24.- - ?????