PDBsum entry 2leh

Protein binding

PDB id: 2leh

Contents

Protein chains

189 a.a.

26 a.a.

PDB id:

2leh

Name:

Protein binding

Title:

Solution structure of the core smn-gemin2 complex

Structure:

Survival of motor neuron protein-interacting protein 1. Chain: a. Fragment: unp residues 95-280. Synonym: smn-interacting protein 1, component of gems 2, gemin-2. Engineered: yes. Survival motor neuron protein. Chain: b. Fragment: unp residues 26-51. Synonym: component of gems 1, gemin-1.

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: sip1, gemin2. Expressed in: escherichia coli. Expression_system_taxid: 469008. Gene: smn1, smn, smnt, smn2, smnc.

NMR struc:

32 models

Authors:

K.L.Sarachan,K.Valentine,K.Gupta,V.Moorman,J.Gledhill,M.Bernens, C.Tommos,A.J.Wand,G.Van Duyne

Key ref:

K.L.Sarachan et al. (2012). Solution structure of the core SMN-Gemin2 complex. Biochem J, 445, 361-370. PubMed id: 22607171

Date:

15-Jun-11 Release date: 27-Jun-12

Protein chain

O14893  (GEMI2_HUMAN) -  Gem-associated protein 2 from Homo sapiens

Seq: 280 a.a.

Struc: 189 a.a.

Protein chain

Q16637  (SMN_HUMAN) -  Survival motor neuron protein from Homo sapiens

Seq: 294 a.a.

Struc: 26 a.a.

Enzyme reactions

• Enzyme class: Chains A, B: E.C.?

Biochem J 445:361-370 (2012)

PubMed id: 22607171

Solution structure of the core SMN-Gemin2 complex.

K.L.Sarachan, K.G.Valentine, K.Gupta, V.R.Moorman, J.M.Gledhill, M.Bernens, C.Tommos, A.J.Wand, G.D.Van Duyne.

ABSTRACT

No abstract given.