PDBsum entry 2las

Transcription

PDB id: 2las

Contents

Protein chains

78 a.a.

13 a.a.

PDB id:

2las

Name:

Transcription

Title:

Molecular determinants of paralogue-specific sumo-sim recognition

Structure:

Small ubiquitin-related modifier 1. Chain: a. Synonym: sumo-1, gap-modifying protein 1, gmp1, smt3 homolog 3, sentrin, ubiquitin-homology domain protein pic1, ubiquitin-like protein smt3c, smt3c, ubiquitin-like protein ubl1. Engineered: yes. M-ir2_peptide. Chain: b. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ok/sw-cl.43, smt3c, smt3h3, sumo1, ubl1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Synthetic: yes. Organism_taxid: 9606

NMR struc:

10 models

Authors:

A.Namanja,Y.Li,Y.Su,S.Wong,J.Lu,L.Colson,C.Wu,S.Li,Y.Chen

Key ref:

A.T.Namanja et al. (2012). Insights into high affinity small ubiquitin-like modifier (SUMO) recognition by SUMO-interacting motifs (SIMs) revealed by a combination of NMR and peptide array analysis. J Biol Chem, 287, 3231-3240. PubMed id: 22147707

Date:

20-Mar-11 Release date: 14-Dec-11

Protein chain

P63165  (SUMO1_HUMAN) -  Small ubiquitin-related modifier 1 from Homo sapiens

Seq: 101 a.a.

Struc: 78 a.a.

Protein chain

P49792  (RBP2_HUMAN) -  E3 SUMO-protein ligase RanBP2 from Homo sapiens

Seq: 3224 a.a.

Struc: 13 a.a.*

* PDB and UniProt seqs differ at 2 residue positions (black crosses)

Enzyme reactions

• Enzyme class: Chain B: E.C.2.3.2.- - ?????

J Biol Chem 287:3231-3240 (2012)

PubMed id: 22147707

Insights into high affinity small ubiquitin-like modifier (SUMO) recognition by SUMO-interacting motifs (SIMs) revealed by a combination of NMR and peptide array analysis.

A.T.Namanja, Y.J.Li, Y.Su, S.Wong, J.Lu, L.T.Colson, C.Wu, S.S.Li, Y.Chen.

ABSTRACT

No abstract given.