PDBsum entry 2l8h

RNA

PDB id: 2l8h

Contents

DNA/RNA

Ligands

ARG-L8H

PDB id:

2l8h

Name:

RNA

Title:

Chemical probe bound to HIV tar RNA

Structure:

HIV tar RNA. Chain: a. Engineered: yes

Source:

Synthetic: yes. Synthetic construct. Organism_taxid: 32630. Other_details: in vitro transcription using t7 polymerase

NMR struc:

10 models

Authors:

A.Davidson,D.Begley,C.Lau,G.Varani

Key ref:

A.Davidson et al. (2011). A small-molecule probe induces a conformation in HIV TAR RNA capable of binding drug-like fragments. J Mol Biol, 410, 984-996. PubMed id: 21763501

Date:

12-Jan-11 Release date: 23-Mar-11

DNA/RNA chain

G-G-C-A-G-A-U-C-U-G-A-G-C-C-U-G-G-G-A-G-C-U-C-U-C-U-G-C-C 29 bases

J Mol Biol 410:984-996 (2011)

PubMed id: 21763501

A small-molecule probe induces a conformation in HIV TAR RNA capable of binding drug-like fragments.

A.Davidson, D.W.Begley, C.Lau, G.Varani.

ABSTRACT

No abstract given.