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PDBsum entry 2l4h

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Metal binding protein PDB id
2l4h

 

 

 

 

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Contents
Protein chain
184 a.a.
Metals
_CA ×2
PDB id:
2l4h
Name: Metal binding protein
Title: The solution structure of calcium bound cib1
Structure: Calcium and integrin-binding protein 1. Chain: a. Synonym: cib, calcium- and integrin-binding protein, cibp, calmyrin, DNA-pkcs-interacting protein, kinase-interacting protein, kip, snk- interacting protein 2-28, sip2-28. Engineered: yes
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: cib1, cib, kip, prkdcip. Expressed in: escherichia coli. Expression_system_taxid: 562.
NMR struc: 11 models
Authors: H.Huang,H.J.Vogel
Key ref: H.Huang et al. (2011). Solution structures of Ca2+-CIB1 and Mg2+-CIB1 and their interactions with the platelet integrin alphaIIb cytoplasmic domain. J Biol Chem, 286, 17181-17192. PubMed id: 21388953
Date:
06-Oct-10     Release date:   09-Mar-11    
PROCHECK
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 Headers
 References

Protein chain
Pfam   ArchSchema ?
Q99828  (CIB1_HUMAN) -  Calcium and integrin-binding protein 1 from Homo sapiens
Seq:
Struc:
191 a.a.
184 a.a.
Key:    PfamA domain  Secondary structure  CATH domain

 Enzyme reactions 
   Enzyme class: E.C.?
[IntEnz]   [ExPASy]   [KEGG]   [BRENDA]

 

 
J Biol Chem 286:17181-17192 (2011)
PubMed id: 21388953  
 
 
Solution structures of Ca2+-CIB1 and Mg2+-CIB1 and their interactions with the platelet integrin alphaIIb cytoplasmic domain.
H.Huang, H.Ishida, A.P.Yamniuk, H.J.Vogel.
 
  ABSTRACT  
 
No abstract given.

 

Literature references that cite this PDB file's key reference

  PubMed id Reference
23023331 S.Riazuddin, I.A.Belyantseva, A.P.Giese, K.Lee, A.A.Indzhykulian, S.P.Nandamuri, R.Yousaf, G.P.Sinha, S.Lee, D.Terrell, R.S.Hegde, R.A.Ali, S.Anwar, P.B.Andrade-Elizondo, A.Sirmaci, L.V.Parise, S.Basit, A.Wali, M.Ayub, M.Ansar, W.Ahmad, S.N.Khan, J.Akram, M.Tekin, S.Riazuddin, T.Cook, E.K.Buschbeck, G.I.Frolenkov, S.M.Leal, T.B.Friedman, and Z.M.Ahmed (2012).
Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.
  Nat Genet, 44, 1265-1271.  
The most recent references are shown first. Citation data come partly from CiteXplore and partly from an automated harvesting procedure. Note that this is likely to be only a partial list as not all journals are covered by either method. However, we are continually building up the citation data so more and more references will be included with time.

 

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