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PDBsum entry 2kv9
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Cell adhesion
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PDB id
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2kv9
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Contents |
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* Residue conservation analysis
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PDB id:
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| Name: |
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Cell adhesion
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Title:
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Integrin beta3 subunit in a disulfide linked alphaiib-beta3 cytosolic domain
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Structure:
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Integrin beta-3. Chain: b. Fragment: unp residues 739-788. Synonym: platelet membrane glycoprotein iiia, gpiiia. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: itgb3, gp3a. Expressed in: escherichia coli. Expression_system_taxid: 511693.
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NMR struc:
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20 models
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Authors:
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D.G.Metcalf,J.M.Kielec,K.G.Valentine,A.Wand,J.S.Bennett,D.F.William, D.T.Moore,K.Molnar
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Key ref:
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D.G.Metcalf
et al.
(2010).
NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation.
Proc Natl Acad Sci U S A,
107,
22481-22486.
PubMed id:
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Date:
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10-Mar-10
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Release date:
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12-Jan-11
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PROCHECK
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Headers
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References
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P05106
(ITB3_HUMAN) -
Integrin beta-3 from Homo sapiens
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Seq:
Struc:
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788 a.a.
54 a.a.*
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Key: |
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PfamA domain |
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Secondary structure |
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*
PDB and UniProt seqs differ
at 4 residue positions (black
crosses)
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Proc Natl Acad Sci U S A
107:22481-22486
(2010)
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PubMed id:
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NMR analysis of the alphaIIb beta3 cytoplasmic interaction suggests a mechanism for integrin regulation.
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D.G.Metcalf,
D.T.Moore,
Y.Wu,
J.M.Kielec,
K.Molnar,
K.G.Valentine,
A.J.Wand,
J.S.Bennett,
W.F.DeGrado.
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ABSTRACT
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Links
