PDBsum entry 2glc

Hydrolase

PDB id: 2glc

Contents

Protein chain

327 a.a. *

Ligands

VO4 ×2

Waters ×271

* Residue conservation analysis

Obsolete entry

PDB id:

2glc

Name:

Hydrolase

Title:

Structure of francisella tularensis histidine acid phosphatase bound to orthovanadate

Structure:

Histidine acid phosphatase. Chain: a. Engineered: yes

Source:

Francisella tularensis subsp. Holarctica. Organism_taxid: 119857. Strain: live vaccine strain (lvs). Gene: hap. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.

Resolution:

1.65Å R-factor: 0.196 R-free: 0.219

Authors:

R.L Felts,J.J.Tanner,T.J Reilly

Key ref:

R.L.Felts et al. Structural basis of inhibition for francisella tularensis histidine acid phosphatase. To be published, .

Date:

04-Apr-06 Release date: 10-Apr-07

Protein chain

No UniProt id for this chain

Struc: 327 a.a.

Enzyme reactions

• Enzyme class: E.C.3.1.3.2 - acid phosphatase.
• Reaction: a phosphate monoester + H2O = an alcohol + phosphate

Molecule diagrams generated from .mol files obtained from the KEGG ftp site