PDBsum entry 2fud

Hydrolase

PDB id

2fud

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Contents

			Protein chain

					218 a.a. *

			Ligands

					CRL ×2

			Waters ×311

* Residue conservation analysis

PDB id:

2fud

Links
- PDBe
- RCSB
- MMDB
- JenaLib
- Proteopedia
- CATH
- SCOP
- PDBSWS
- PDBePISA
- CSA
- ProSAT

Name:

Hydrolase

Title:

Human cathepsin s with inhibitor cra-27566

Structure:

Cathepsin s. Chain: a, b. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108

Biol. unit:

Tetramer (from PQS)

Resolution:

1.95Å

R-factor:

0.190

R-free:

0.217

Authors:

J.R.Somoza

Key ref:

J.R.Somoza Human cathepsin s with inhibitor cra-27566. To be published, .

Date:

26-Jan-06

Release date:

01-Aug-06

PROCHECK

	Headers

	References

Protein chains

P25774 (CATS_HUMAN) - Cathepsin S from Homo sapiens

Seq: Struc:					331 a.a. 218 a.a.

Key:

PfamA domain

Secondary structure

CATH domain



		Enzyme reactions

Enzyme class:

E.C.3.4.22.27 - cathepsin S.

[IntEnz] [ExPASy] [KEGG] [BRENDA]

Reaction:

Similar to cathepsin L, but with much less activity on Z-Phe-Arg-|-NHMec, and more activity on the Z-Val-Val-Arg-|-Xaa compound.