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PDBsum entry 2faz
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Contents |
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* Residue conservation analysis
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PDB id:
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Ligase
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Title:
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Ubiquitin-like domain of human nuclear zinc finger protein np95
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Structure:
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Ubiquitin-like containing phd and ring finger domains protein 1. Chain: a, b. Fragment: ubiquitin-like domain. Synonym: inverted ccaat box binding protein of 90 kda, transcription factor icbp90, nuclear zinc finger protein np95, nuclear protein 95, hunp95, ring finger protein 106. Engineered: yes
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Source:
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Homo sapiens. Human. Organism_taxid: 9606. Gene: uhrf1, icbp90, np95, rnf106. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
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Biol. unit:
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Tetramer (from
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Resolution:
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2.00Å
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R-factor:
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0.220
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R-free:
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0.252
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Authors:
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J.R.Walker,L.Wybenga-Groot,R.S.Doherty,P.J.Finerty Jr.,E.Newman, F.M.Mackenzie,J.Weigelt,M.Sundstrom,C.Arrowsmith,A.Edwards, A.Bochkarev,S.Dhe-Paganon,Structural Genomics Consortium (Sgc)
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Key ref:
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J.R.Walker
et al.
Ubiquitin-Like domain of human nuclear zinc finger protein np95.
To be published,
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Date:
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08-Dec-05
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Release date:
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20-Dec-05
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PROCHECK
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Headers
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References
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Q96T88
(UHRF1_HUMAN) -
E3 ubiquitin-protein ligase UHRF1 from Homo sapiens
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Seq:
Struc:
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793 a.a.
77 a.a.
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Key: |
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PfamA domain |
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Secondary structure |
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CATH domain |
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Enzyme class:
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E.C.2.3.2.27
- RING-type E3 ubiquitin transferase.
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Reaction:
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S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N6- ubiquitinyl-[acceptor protein]-L-lysine
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Links
