PDBsum entry 2e7h

Transferase, signaling protein

PDB id: 2e7h

Contents

Protein chain

109 a.a. *

* Residue conservation analysis

PDB id:

2e7h

Name:

Transferase, signaling protein

Title:

Solution structure of the second fn3 domain from human ephrin type-b receptor 4

Structure:

Ephrin type-b receptor 4. Chain: a. Fragment: fn3 domain. Synonym: tyrosine-protein kinase receptor htk. Engineered: yes

Source:

Homo sapiens. Human. Organism_taxid: 9606. Gene: ephb4, htk. Other_details: cell free protein synthesis

NMR struc:

20 models

Authors:

X.R.Qin,F.Hayashi,S.Yokoyama,Riken Structural Genomics/proteomics Initiative (Rsgi)

Key ref:

X.R.Qin et al. Solution structure of the second fn3 domain from human ephrin type-B receptor 4. To be published, .

Date:

10-Jan-07 Release date: 10-Jul-07

Protein chain

P54760  (EPHB4_HUMAN) -  Ephrin type-B receptor 4 from Homo sapiens

Seq: 987 a.a.

Struc: 109 a.a.*

* PDB and UniProt seqs differ at 13 residue positions (black crosses)

Enzyme reactions

• Enzyme class: E.C.2.7.10.1 - receptor protein-tyrosine kinase.
• Reaction: L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H⁺

Molecule diagrams generated from .mol files obtained from the KEGG ftp site